GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9815354 | 1 | rs9865127 | chr3:41807448 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.16 | 5.5E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9865780 | chr3:41895802 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9866092 | chr3:41895967 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9866759 | chr3:41758418 | ULK4 | chr3:41288091-42003660:- | 1.03 | 11.64 | 5.41E-20 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9867627 | chr3:41795841 | ULK4 | chr3:41288091-42003660:- | -0.94 | -9.12 | 1.25E-14 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9869207 | chr3:41878661 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9869282 | chr3:41756064 | ULK4 | chr3:41288091-42003660:- | 1.03 | 11.64 | 5.41E-20 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9869440 | chr3:41763155 | ULK4 | chr3:41288091-42003660:- | 1.01 | 11.17 | 5.4E-19 | Diastolic blood pressure |
| THYM | cis | rs10935120 | 1 | rs9869981 | chr3:134248801 | ANAPC13 | chr3:134196547-134204865:- | 0.58 | 8.01 | 2.88E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs9869981 | chr3:134248801 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6.04 | 2.93E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs9871305 | chr3:134213538 | ANAPC13 | chr3:134196547-134204865:- | 0.59 | 8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs9871305 | chr3:134213538 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 5.87 | 6.33E-8 | Height |
| THYM | cis | rs9815354 | 1 | rs9873207 | chr3:41884750 | ULK4 | chr3:41288091-42003660:- | 0.96 | 9.51 | 1.88E-15 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9874513 | chr3:41909508 | ULK4 | chr3:41288091-42003660:- | 0.95 | 9.28 | 5.58E-15 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9874975 | chr3:41764300 | ULK4 | chr3:41288091-42003660:- | 1.03 | 11.59 | 7.14E-20 | Diastolic blood pressure |